BMS-8

BMS-8
  • CAS No.:1675201-90-7
  • Grade:98.0%
  • Formula:C27H28BrNO3
  • M.W.:494.42
  • Solvent:≥ 2.08 mg/mL (4.21 mM); Clear solution

Overview

BMS-8 inhibits the PD-1/PD-L1 interaction with IC 50 of 7.2 μM. BMS-8, binds directly to PD-L1 and induces formation of PD-L1 homodimers, which in turn prevents the interaction with PD-1 .

Application

Products | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Gastric Cancer | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Disease Areas > Ovarian Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > PD-1/PD-L1

Product Information

  • Catalog No.: HY-116274
  • CAS No.: 1675201-90-7
  • Molecular Formula: C27H28BrNO3
  • Molecular Weight: 494.42
  • Purity: 98.0%
  • Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
  • Solubility: ≥ 2.08 mg/mL (4.21 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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