(S)-(−)-Perillyl alcohol

Overview

(S)-(-)-Perillyl alcohol, a monoterpene, is an orally active farnesyl transferase and geranylgeranyl transferase inhibitor. (S)-(-)-Perillyl alcohol up-regulates the mannose-6-phosphate receptor, facilitating TGF-β1 activation and cytostasis,. (S)-(-)-Perillyl alcohol induces apoptosis in cancer cells, modulates cyclin D1 and AP-1 activity. (S)-(-)-Perillyl alcohol exhibits antitumor activity against sarcoma tumors in mice. (S)-(-)-Perillyl alcohol can be used for the research of squamous cell carcinoma of the esophagus and sarcoma 180.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Melanoma | Products > Disease Areas > Squamous Cell Carcinoma | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Farnesyl Transferase | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Endogenous Metabolite

Product Information

• Catalog No.: HY-116514
• CAS No.: 18457-55-1
• Molecular Formula: C10H16O
• Molecular Weight: 152.24
• Purity: 97.0%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 5 mg/mL (32.84 mM); Clear solution
• Availability: In-stock

Source

Original product source