AR420626

Overview

AR420626 is a selective agonist of free fatty acid receptor 3 ( FFAR3 ) ( IC 50 =117 nM). AR420626 has anti-inflammatory, anticancer and antidiabetic activities. AR420626 improves neurogenic diarrhea by inhibiting nAChR mediated neural pathways. AR420626 inhibits the growth of HepG2 xenografts and inhibits the proliferation of hepatoma cells by inducing apoptosis . AR420626 also suppresses allergic asthma and eczema and has the ability to activate GPR41 to increase Ca 2+ signal-mediated glucose uptake and improve diabetes.

Application

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Product Information

• Catalog No.: HY-116522
• CAS No.: 1798310-55-0
• Molecular Formula: C21H18Cl2N2O3
• Molecular Weight: 417.29
• Purity: 98.40%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2 mg/mL (4.79 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source