TTK21

Overview

TTK21 is an activator of the histone acetyltransferases CBP/p300 . TTK21 passes the blood–brain barrier, induces no toxicity, and reaches different parts of the brain when conjugated to glucose-based carbon nanosphere (CSP). TTK21 has beneficial implications for the brain functions of neurogenesis and long-term memory.CSP-TTK21 can ameliorate Aβ-impaired long-term potentiation (LTP). CSP-TTK21 may enhance the transcription of genes that promote synaptic health and cognitive function. CSP-TTK21 is orally effective and leads to improvements in motor functions, histone acetylation dynamics in a spinal injury rat model.

Application

Products | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Lung Fibrosis | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Histone Acetyltransferase

Product Information

• Catalog No.: HY-116673
• CAS No.: 709676-56-2
• Molecular Formula: C17H15ClF3NO2
• Molecular Weight: 357.75
• Purity: 99.39%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.99 mM); Clear solution
• Availability: In-stock

Source

Original product source