DCG066

Overview

DCG066 is an inhibitor of lysine methyltransferase G9a . DCG066 can bind directly to G9a and inhibit methyltransferase activity in vitro. DCG066 decreases di-methylation levels of histone H3 lysine 9 ( H3K9Me2 ), inhibits cell proliferation and induces cell apoptosis . DCG066 displays low cytotoxicity in leukemia cell lines with high levels of G9a expression, including K562.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Histone Methyltransferase | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-116971
• CAS No.: 494786-13-9
• Molecular Formula: C30H31F6N3O2
• Molecular Weight: 579.58
• Purity: 99.78%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (8.63 mM); Clear solution
• Availability: In-stock

Source

Original product source