BMY 7378 free base

Overview

BMY 7378 (free base) is a selective antagonist of α 1D -adrenoceptor (α 1D -AR). BMY 7378 (free base) binds to membranes expressing the cloned rat α 1D -AR with a >100-fold higher affinity ( K i =2 nM) than binding to either the cloned rat α 1A -AR (K i =800 nM) or the hamster α 1B -AR ( K i =600 nM). BMY 7378 (free base) is a 5-HT 1A receptor partial agonist.

Application

Products | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Adrenergic Receptor | Products > Signaling Pathways > 5-HT Receptor

Product Information

• Catalog No.: HY-116982
• CAS No.: 21102-94-3
• Molecular Formula: C22H31N3O3
• Molecular Weight: 385.50
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source