PF-4191834

Overview

PF-4191834 (PF-04191834) is an orally active, noniron chelating, and non-redox inhibitor of the 5-Lipoxygenase ( 5-LOX ) ( IC 50 =229 nM), displays ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX , shows no activity toward the cyclooxygenase enzymes , and is effective in inflammation and pain.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Prostate Cancer | Products > Disease Areas > Urogenital Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Lipoxygenase

Product Information

• Catalog No.: HY-117048
• CAS No.: 1029317-21-2
• Molecular Formula: C22H23N3O2S
• Molecular Weight: 393.50
• Purity: 99.48%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.5 mg/mL (6.35 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source