PF-4191834

CAS No.：1029317-21-2
Grade：99.48%
Formula：C22H23N3O2S
M.W.：393.50
Solvent：2.5 mg/mL (6.35 mM); Suspended solution; Need ultrasonic

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Overview

PF-4191834 (PF-04191834) is an orally active, noniron chelating, and non-redox inhibitor of the 5-Lipoxygenase ( 5-LOX ) ( IC 50 =229 nM), displays ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX , shows no activity toward the cyclooxygenase enzymes , and is effective in inflammation and pain.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Prostate Cancer | Products > Disease Areas > Urogenital Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Lipoxygenase

Product Information

Catalog No.: HY-117048
CAS No.: 1029317-21-2
Molecular Formula: C22H23N3O2S
Molecular Weight: 393.50
Purity: 99.48%
Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Solubility: 2.5 mg/mL (6.35 mM); Suspended solution; Need ultrasonic
Availability: In-stock

Source

Original product source

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