ZM 253270 is a species-selective non-peptide NK-2 receptor (NK-2R) antagonist. ZM 253270 competitively inhibits the binding of [ 3 H]NKA to native or cloned NK-2R from hamster bladder ( K i =2 nM), but has a weaker inhibitory effect (48-fold) on the binding of [ 3 H]NKA to cloned human NK-2R .
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Neurokinin Receptor
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