AMG131

AMG131
  • CAS No.:315224-26-1
  • Grade:98.99%
  • Formula:C21H12Cl4N2O3S
  • M.W.:514.21
  • Solvent:≥ 2.08 mg/mL (4.05 mM); Clear solution

Overview

AMG131 (INT131) is a potent non-thiazolidinedione (TZD) selective peroxisome proliferator-activated receptor γ modulator ( SPPARM ). AMG131 binds to PPARγ within the same binding pocket as the TZDs, but occupies a unique space in the pocket and contacts the receptor at distinct points from the TZDs. AMG131 is promising for research of type-2 diabetes mellitus.

Application

Products | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Depression | Products > Disease Areas > Digestive System Inflammation | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Obesity | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > PPAR

Product Information

  • Catalog No.: HY-117103
  • CAS No.: 315224-26-1
  • Molecular Formula: C21H12Cl4N2O3S
  • Molecular Weight: 514.21
  • Purity: 98.99%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Solubility: ≥ 2.08 mg/mL (4.05 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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