PF-06685249

Overview

PF-06685249 (PF-249) is a potent and orally active allosteric AMPK activator with an EC 50 of 12 nM for recombinant AMPK α1β1γ1 . PF-06685249 improves renal function in ZSF-1 rats with diabetic nephropathy. PF-06685249 can be used for diabetic nephropathy research.

Application

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Product Information

• Catalog No.: HY-117623
• CAS No.: 1467059-70-6
• Molecular Formula: C17H16ClN3O3
• Molecular Weight: 345.78
• Purity: 98.00%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source