PARP14 inhibitor H10

Overview

PARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 ( IC 50 =490 nM), over other PARPs (≈24 fold over PARP1 ). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PARP | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-117889
• CAS No.: 2084811-68-5
• Molecular Formula: C24H27N7O7S
• Molecular Weight: 557.58
• Purity: 99.46%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (3.73 mM); Clear solution
• Availability: In-stock

Source

Original product source