HJC0197

Overview

HJC0197 is a potent Epac1 (exchange protein directly activated by cAMP 1) and Epac2 ( IC 50 =5.9 μM for Epac2) antagonist. HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 inhibits Epac1-mediated Rap1-GDP exchange activity at 25 μM in the presence of equal concentration of cAMP.

Application

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Product Information

• Catalog No.: HY-117958
• CAS No.: 1383539-73-8
• Molecular Formula: C19H21N3OS
• Molecular Weight: 339.45
• Purity: 99.62%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (7.36 mM); Clear solution
• Availability: In-stock

Source

Original product source