CPS-11 (N-(Hydroxymethyl)thalidomide) a Thalidomide ( HY-14658 ) analogue, is a potent anti-cancer agent. CPS-11 inhibits NF-κB , activates NFAT , and repress cytokine expression through elevated ROS . CPS-11 exhibits a wider activity spectrum and higher potency against MM (multiple myeloma) cell lines.
Products | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Nuclear Factor of activated T Cells (NFAT) | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Reactive Oxygen Species (ROS)
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