PKR-IN-C51

Overview

PKR-IN-C51 is an ATP-competitive protein kinase R (PKR) inhibitor with a human IC 50 of 9 μM and a human K i of 3.4 μM. PKR-IN-C51 blocks the activation of PKR, inhibits intracellular PKR activation in primary mouse macrophages, and shows no obvious cytotoxicity. PKR-IN-C51 can be used in studies related to the regulation of PKR-mediated signaling pathways.

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Others | Products > Signaling Pathways > Pyruvate Kinase

Product Information

• Catalog No.: HY-118131
• CAS No.: 1314594-23-4
• Molecular Formula: C23H21N5
• Molecular Weight: 367.45
• Purity: 99.79%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.08 mg/mL (5.66 mM); Clear solution
• Availability: In-stock

Source

Original product source