Org-12962 is a potent, selective and brain-penetrant and 5-HT 2C receptor agonist with a pEC 50 value of 7.01. Org-12962 also exhibits high effacy for the 5-HT 2A and 5-HT 2B receptor with pEC 50 s of 6.38 and 6.28, respectively.Org-12962 displays antiaversive effects in a rat model of panic-like anxiety.
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