YM928

Overview

YM928 is an orally active and noncompetitive α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist. YM928 inhibits AMPA receptor -mediated toxicity in primary rat hippocampal cultures with an IC 50 value of 2 μM. YM928 blocks AMPA-induced intracellular calcium influx with an IC 50 value of 3 μM and antagonizes AMPA-induced inward currents with an IC 50 value of 1 μM. YM928 is promising for research of neurological disorders.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > iGluR

Product Information

• Catalog No.: HY-118814
• CAS No.: 190842-36-5
• Molecular Formula: C14H10ClN3OS
• Molecular Weight: 303.77
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source