KF26777 (free base) is a potent and selective adenosine A3 receptor antagonist with an K i value of 0.2 nM and possesses 9000-, 2350- and 3100-fold selectivity against adenosine A1 , A2A and A2B receptors , respectively. KF26777 (free base) potently inhibits the [125I]AB-MECA binding to adenosine A3 receptors . KF26777 (free base) is promising for research of brain ischemia and inflammatory disease including asthma.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Adenosine Receptor
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