AZ13711265 is an orally active PAK1 inhibitor with high selectivity. AZ13711265 has IC 50 values of 0.58 nM and 0.11 µM for PAK1 and pPAK1 , respectively. AZ13711265 has low lipophilicity and low clearance, and can be used as an in vivo probe compound for PAK1 . AZ13711265 can be used in the study of cancer .
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