AZ084

Overview

AZ084 is a potent, selective, allosteric and oral active CCR8 allosteric antagonist, with a K i of 0.9 nM. Has potential to treat asthma. AZ084 restrains the formation of the immunologically tolerant pre-metastatic niche (PMN) and tumor cells metastasis in lung by downregulating Treg differentiation. AZ084 can be used in studies of asthma and cancer .

Application

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Product Information

• Catalog No.: HY-119217
• CAS No.: 929300-19-6
• Molecular Formula: C26H34N4O2
• Molecular Weight: 434.57
• Purity: 99.70%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (4.79 mM); Clear solution
• Availability: In-stock

Source

Original product source