VU0152099

Overview

VU0152099 is a potent, selective and brain-penetrant mAChR M4 positive allosteric modulator with an EC 50 of 0.4 µM for rat M4 receptor. VU0152099 is inactive for other mAChR subtypes or other GPCRs. VU0152099 has no agonist activity but potentiated responses of M4 to acetylcholine.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > mAChR

Product Information

• Catalog No.: HY-119226
• CAS No.: 612514-42-8
• Molecular Formula: C18H17N3O3S
• Molecular Weight: 355.41
• Purity: 98.39%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 1.25 mg/mL (3.52 mM); Clear solution
• Availability: In-stock

Source

Original product source