CMLD010509

Overview

CMLD010509 (SDS-1-021) is a highly specific inhibitor of the oncogenic translation program supporting multiple myeloma (MM)-including key oncoproteins such as MYC, MDM2 , CCND1, MAF, and MCL-1 . CMLD010509 (SDS-1-021) shows an IC 50 below 10 nM for most MM cell lines and induces apoptosis . CMLD010509 (SDS-1-021) is a potent and selective translation inhibitor through an eIF4E phosphorylation-independent mechanism.

Application

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Product Information

• Catalog No.: HY-119271
• CAS No.: 256497-58-2
• Molecular Formula: C27H26BrNO7
• Molecular Weight: 556.40
• Purity: 99.11%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 3 mg/mL (5.39 mM); Clear solution
• Availability: In-stock

Source

Original product source