CM-545, the cis-isomer of CM-414 ( HY-119316 ), is a dual inhibitor of PDE5 , HDAC1 , HDAC2 , HDAC3 , and HDAC6 with pIC 50 values of 7.47, 6.65, 6.14, 6.55, and 6.84, repectively.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > HDAC | Products > Signaling Pathways > Phosphodiesterase (PDE)
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