MRL-871

Overview

MRL-871 (compound 3) is a potent and allosteric retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonists with an IC 50 of 12.7 nM. MRL-871 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells.

Application

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Product Information

• Catalog No.: HY-119464
• CAS No.: 1392809-08-3
• Molecular Formula: C22H12ClF3N2O3
• Molecular Weight: 444.79
• Purity: 99.11%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source