SB251023 is a β3-adrenergic receptor agonist with pEC 50 values of 7.14 and 6.91 for the β3a- and β3b-adrenergic receptors , respectively. SB251023 is capable of modulating cyclic AMP levels and extracellular acidification rate (EAR) in cells. It has potential application value in the study of cardiovascular diseases and metabolic-related disorders.
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