Atiprosine

Overview

Atiprosine (AY-28228) is an orally effective selective α1-adrenergic receptor antagonist with a pA 2 value of 8.11. Atiprosine exhibits antagonistic activity against α2-adrenergic receptors ( α1-adrenergic receptor ), 5-HT₂ receptors (5-HT₂ receptor) , and H₁ receptors ( H₁ receptor ). The pA 2 values for these receptors are 6.04, 6.87, and 7.32 respectively. Atiprosine has antihypertensive and hypotensive effects in rats, dogs, and monkeys. It can be used for research on cardiovascular and mental disorders.

Application

Products | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Hypertension | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Adrenergic Receptor | Products > Signaling Pathways > 5-HT Receptor | Products > Signaling Pathways > Histamine Receptor

Product Information

• Catalog No.: HY-119854
• CAS No.: 89303-63-9
• Molecular Formula: C20H29N3
• Molecular Weight: 311.46
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source