GNE-207

Overview

GNE-207 is a potent, selective and orally bioavailable inhibitor of the bromodomain of CBP , with an IC 50 of 1 nM, exhibits a selectively index of >2500-fold against BRD4 (1). GNE-207 shows excellent CBP potency, with an EC 50 of 18 nM for MYC expression in MV-4-11 cells.

Application

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Product Information

• Catalog No.: HY-120028
• CAS No.: 2158266-58-9
• Molecular Formula: C29H30N6O3
• Molecular Weight: 510.59
• Purity: 99.94%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 5 mg/mL (9.79 mM); Clear solution
• Availability: In-stock

Source

Original product source