VU0418506 is a selective positive allosteric modulator of mGlu 4 , with EC 50 values of 68 nM and 46 nM for hmGlu 4 and rmGlu 4 , respectively. VU0418506 exhibits antiparkinsonian activity.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > mGluR
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