(R)-KMH-233

Overview

(R)-KMH-233 is the isomer of KMH-233 ( HY-120139 ), and can be used as an experimental control. KMH-233 , a potent, reversible and selective l-type amino acid transporter 1 (LAT1) inhibitor, inhibits the uptake of LAT1 substrate, l-leucin (IC 50 =18 μM) as well as cell growth. KMH-233 significantly potentiates the efficacy of Bestatin and Cisplatin even at low concentrations (25 μM).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > ASCT

Product Information

• Catalog No.: HY-120139A
• CAS No.: 2994330-89-9
• Molecular Formula: C32H25N7O5
• Molecular Weight: 587.58
• Purity: 99.98%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source