NNC 05-2090 is a GABA uptake inhibitor and inhibitor of the β-GABA transporter ( BGT-1 ) ( IC 50 sub>: 10.6 μM). NNC 05-2090 also inhibits mGAT2 with a K i value of 1.4 μM. NNC 05-2090 has anticonvulsant activity and can be used in the study of epilepsy and neurological diseases.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > GABA Receptor
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