XY018

CAS No.：1873358-87-2
Grade：99.68%
Formula：C23H15F7N2O4
M.W.：516.37
Solvent：≥ 2.5 mg/mL (4.84 mM); Clear solution

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Overview

XY018 is a potent ROR-γ -selective antagonist. XY018 inhibits ROR-γ constitutive activity in 293T cells with high potency ( EC 50 , 190 nM). XY018 binds to the ROR-γ hydrophobic ligand binding domain (LBD).

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > ROR

Product Information

Catalog No.: HY-120210
CAS No.: 1873358-87-2
Molecular Formula: C23H15F7N2O4
Molecular Weight: 516.37
Purity: 99.68%
Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
Solubility: ≥ 2.5 mg/mL (4.84 mM); Clear solution
Availability: In-stock

Source

Original product source

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