PU141

Overview

PU141 is a selected pyridoisothiazolone HAT inhibitor. PU141 is selective toward CBP and p300 . PU141 induces cellular histone hypoacetylation and inhibits growth of several neoplastic cell lines originating from different tissues. Anticancer activity.

Application

Products | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Lung Fibrosis | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Histone Acetyltransferase

Product Information

• Catalog No.: HY-120290
• CAS No.: 168334-34-7
• Molecular Formula: C14H9F3N2OS
• Molecular Weight: 310.29
• Purity: 99.96%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 5 mg/mL (16.11 mM); Clear solution; Need ultrasonic and warming and heat to 80°C
• Availability: In-stock

Source

Original product source