T-1101

Overview

T-1101 (TAI-95) is an orally active inhibitor for mitose regulating highly expressed oncoprotein 1 (Hec1) . T-1101 blocks the interaction between Hec1 and NEK2 , exhibits cytotoxicity in human liver cancer cells with GI 50 of 15-70 nM. T-1101 induces apoptosis in Huh-7. T-1101 exhibits antitumor efficacy in mouse models.

Application

Products | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > NEKs

Product Information

• Catalog No.: HY-120356
• CAS No.: 1438638-83-5
• Molecular Formula: C24H23N5O3S2
• Molecular Weight: 493.60
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source