BMS-871

Overview

BMS-871 is an orally active pan- Notch inhibitor with IC 50 values ​​of 4/1/4/3 nM for Notch1/2/3/4 , respectively. BMS-871 significantly inhibited the proliferation of TALL-1 and MDA-MB-157 cells and demonstrated significant antitumor activity in T-acute lymphoblastic leukemia and triple-negative breast cancer xenograft models. BMS-871 can be used to study leukemia and breast cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Notch

Product Information

• Catalog No.: HY-120372
• CAS No.: 1584631-89-9
• Molecular Formula: C29H27F3N4O3
• Molecular Weight: 536.54
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source