GZ-389988 is a potent pan-TRK inhibitor with IC 50 values of 0.3, 0.1, and 0.5 nM for TRKA , TRKB , and TRKC , respectively. GZ-389988 can be used to study NTRK fusion-positive tumors.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Trk Receptor
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