JP-153

Overview

JP-153 is the Src-FAK-Paxillin signaling inhibitor. JP-153 inhibits Src-dependent phosphorylation of paxillin (Y118) and downstream activation of Akt (S473). JP-153 reduces VEGF-induced migration and proliferation in retinal endothelial cells. JP-153 can be uesd for the study of neovascular eye disease.

Application

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Product Information

• Catalog No.: HY-120417
• CAS No.: 1802937-26-3
• Molecular Formula: C21H19NO5
• Molecular Weight: 365.38
• Purity: 99.45%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: 4 mg/mL (10.95 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source