Ponatinib-d 8

Overview

Ponatinib-d 8 (AP24534-d 8 ) is a deuterium labeled Ponatinib. Ponatinib (AP24534) is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα , VEGFR2, FGFR1, and Src , respectively.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Autophagy | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Bcr-Abl | Products > Signaling Pathways > PDGFR | Products > Signaling Pathways > VEGFR | Products > Signaling Pathways > FGFR | Products > Signaling Pathways > Src | Products > Signaling Pathways > Autophagy

Product Information

• Catalog No.: HY-12047S
• CAS No.: 1562993-37-6
• Molecular Formula: C29H19D8F3N6O
• Molecular Weight: 540.61
• Purity: 99.16%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source