Chelerythrine chloride

Overview

Chelerythrine chloride is a potent, cell-permeable inhibitor of protein kinase C , with an IC 50 of 660 nM. Chelerythrine chloride inhibits the Bcl-XL-Bak BH3 peptide binding with IC 50 of 1.5 μM and displaces Bax from Bcl-XL . Chelerythrine chloride induces apoptosis and autophagy .

Application

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Product Information

• Catalog No.: HY-12048
• CAS No.: 3895-92-9
• Molecular Formula: C21H18ClNO4
• Molecular Weight: 383.82
• Purity: 99.11%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 0.44 mg/mL (1.15 mM); Clear solution
• Availability: In-stock

Source

Original product source