L-674573 is a quinoline leukotriene synthesis inhibitor, inhibiting Calcimycin ( HY-N6687 )- and N-Formyl-Met-Leu-Phe ( HY-P0224 )-induced leukotriene production with IC 50 s of 100 nM and 50 nM, respectively. L-674573 selectively inhibits Calcimycin - and N-Formyl-Met-Leu-Phe -induced 5-lipoxygenase translocation.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Leukotriene Receptor | Products > Signaling Pathways > Lipoxygenase
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