ML169 (VU0405652) is a potent, selective and brain penetrant positive allosteric modulator (PAM) of M 1 mAChR , with an EC 50 of 1.38 µM. ML169 is a MLPCN probe and can be used for Alzheimer’s disease.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > mAChR
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