激酶与磷酸化通路的抑制剂、激活剂及调节剂。
Win 47338 (compound 14) is a control compound of inhibitors of the mitotic kinase monopolar spindle MPS1 and Aurora...
Momelotinib (dihydrochloride) is a JAK1/JAK2 inhibitor that also antagonizes ACVR1 , leading to downregulation of...
4,5,6,7-Tetrabromobenzimidazole is a selective and ATP competitive CK2 ( casein kinase 2) inhibitor.
1-Phenylindole (Compound 8) is a 1-Phenylbenzimidazole analogue. 1-Phenylindole shows IC 50 values of >50 μM and >50...
5-Bromothiazol-2-amine (Compound 54) is a simple amino. 5-Bromothiazol-2-amine shows an IC 50 of >10 µM against...
Lamalbid is a natural product that can be found in Lantana montevidensis . Lamalbid inhibits ROS generation.
AZ7550 -d 5 is the deuterium labeled AZ7550 ?( HY-B0794 ). AZ7550 , an active metabolite of Osimtinib (AZD9291...
CK1-IN-5 (compound B-AZ) is an inhibitor of CK1 . CK1-IN-5 lengthened the circadian period by inhibits AtCKL3/AtCKL4...
3-Azetidinemethanol hydrochloride, an intermediate, can be used in the synthesis of SHP2 inhibitor .
Rigosertib (ON-01910) is a biochemical reagent that can be used as a biological material or organic compound for...
TPKI-39 is a DDR1 , DDR2 , and FLT1 inhibitor, with a human DDR1 IC 50 of 380 nM, human DDR1 K a of 24 nM, human...
CK1γ-IN-1 is a non-selective CK1 kinase inhibitor with IC 50 values of 780 nM, 570 nM and 990 nM against human...
FP1-24 is a non-selective CK1 kinase inhibitor, with IC 50 values of 40 nM, 10 nM, 10 nM, and 40 nM against human...
AKI-062a is a non-selective kinase inhibitor, such as a CK1γ inhibitor. AKI-062a binds to and inhibits WNT pathway...
DDC4002 is a selective EGFR inhibitor. DDC4002 has inhibitory activity against the L858R/T790M mutant EGFR subtype (...
CEP-28122 mesylate hydrochloride, a diaminopyrimidine derivative, is a potent, selective, and orally active ALK...
LDN-193688 (Compound 26) is a ALK2 inhibitor, with IC₅₀ values of 104, 18, 235, 1530, and 1080 nM against ALK1...
HPK1-IN-61 (Compound 1) is an inhibitor of hematopoietic progenitor kinase 1 (HPK1) ( K i = 0.4 nM) and an inhibitor...
CDD-2211 is a STK33 inhibitor, with a K d of 0.018 nM and an IC 50 of 5 nM. CDD-2211 has relatively weak inhibitory...
CDD-2210 is a STK33 inhibitor, with a K d of 0.1 nM and an IC 50 of 38 nM. CDD-2210 has relatively weak inhibitory...
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