用于神经系统及神经退行性疾病研究的化合物。
E0199 is a novel potent dual-target K V 7/Na V modulator that activates the K V 7 channel (K V 7.2/7.3 ( EC 50 =...
Teoprolol is a β-adrenergic receptor blocker.
Huperzine B is a Lycopodium alkaloid isolated from Huperzia serrata and a highly selective acetylcholinesterase (...
Escholtzine is an Alkaloid. Escholtzine can be isolated from Eschscholzia californica . Escholtzine is a CYP3A4...
Eptapirone (F11440) is a potent, selective and orally active 5-HT 1A receptor agonist ( pK i = 8.33). Eptapirone can...
GYKI-47261 dihydrochloride is a competitive, orally active, and selective AMPA receptor antagonist with an IC 50 of...
Papaveroline is a Fyn tyrosine kinase inhibitor, Na + ,K + -ATPase inhibitor with an I50 of 0.20 mM, Mg 2+ -ATPase...
Bambuterol hydrochloride ((±)-Bambuterol hydrochloride; KWD-2183 hydrochloride) is a long acting beta-adrenoceptor...
RDS-04-010 is an atypical dopamine transporter ( DAT ) inhibitor. RDS-04-010 has the effect of inhibiting cocaine...
4-Chloroethamphetamine hydrochloride is an amphetamine.
Axelopran sulfate is an opioid receptor antagonist with pKi values of 9.8, 8.8 and 9.9 for human recombinant μ and δ...
Terodiline, an antispasmodic agent, blocks hERG current with the IC 50 of 375 nM. Terodiline has both...
LY2023-001 is a potent G2019S LRRK2 inhibitor with an IC 50 of 12.9 nM. LY2023-001 formed stable hydrogen bonds with...
AP-6 is a selective inhibitor of TMEM175 with activity in modulating lysosomal function. Acute inhibition of TMEM175...
Flupentixol is an orally active D 1 /D 2 dopamine receptor antagonist and new PI3K inhibitor ( PI3Kα IC 50 =127 nM)....
Cav 3.2 inhibitor 1 is a T-type calcium channel inhibitor with little binding affinity to dopamine D2 receptors. Cav...
Zonampanel (YM 872) is a selective antagonist of the glutamate receptor subtype...
Befiradol (NLX-112) is a highly selective 5-HT 1 A receptor agonist that acts on both presynaptic and postsynaptic...
BSc3094 is a Tau aggregation inhibitor. BSc3094 can be used for the research of Alzheimer's disease (AD).
TFEB activator 1 is an orally effective, mTOR-independent activator of TFEB . TFEB activator 1 significantly...
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