SR-14968

Overview

SR-14968 is a full, allosteric and non-competitive MOR agonist, with an EC 50 of 88 nM for MOR in mouse brainstem. SR-14968 stabilizes MOR in a G protein signaling state that is resistant to washout but reversible by antagonists. SR-14968 induces respiratory depression in mice. SR-14968 can be used in pain-related research.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Pain | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Opioid Receptor

Product Information

• Catalog No.: HY-185356
• CAS No.: 2133455-40-8
• Molecular Formula: C20H20BrCl2N3O
• Molecular Weight: 469.20
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source