PF 06409577

Overview

PF 06409577 is a potent and selective allosteric activator of AMPK (EC50 values are 7 and >40000 nM for AMPKα1β1γ1 and AMPKα1β2γ1, respectively) for the potential treatment of diabetic nephropathy. PF-06409577 showed efficacy in a preclinical model of diabetic nephropathy.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Endocrinology and Metabolic Disease | AMPK

Product Information

• Catalog No.: B2693-170035
• CAS No.: 1467057-23-3
• Molecular Formula: C19H16ClNO3
• Molecular Weight: 341.79
• Purity: ≥98% by HPLC
• Storage: Store in a cool and dry place (or refer to the Certificate of Analysis).

Source

Original product source