VH-298

Overview

VH-298 is a high-affinity inhibitor of E3 ubiquitin ligase VHL (Kd value of 80-90 nM) that could block VHL and HIF-α interactions. VH-298 can be used in PROTAC technology.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Inflammation / Immunology | E1/E2/E3 Enzyme

Product Information

• Catalog No.: B2693-170543
• CAS No.: 2097381-85-4
• Molecular Formula: C₂₇H₃₃N₅O₄S
• Molecular Weight: 523.65
• Purity: ≥98% by HPLC
• Storage: Powder, -20°C, 3 years; 4°C, 2 years; In solvent, -80°C, 6 months; -20°C, 1 month
• Solubility: DMSO: ≥ 83.3 mg/mL (159.08 mM)

Source

Original product source