RO5263397

Overview

RO5263397 is a potent, selective, and orally available TAAR1 agonist, with EC 50 s of 17 and 35 nM for human TAAR1 and rat TAAR1, respectively. RO5263397 regulates wakefulness and EEG spectral composition. Antidepressant-like effect.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Depression | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Trace Amine-associated Receptor (TAAR)

Product Information

• Catalog No.: HY-108015
• CAS No.: 1357266-05-7
• Molecular Formula: C10H11FN2O
• Molecular Weight: 194.21
• Purity: 99.10%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 6.5 mg/mL (33.47 mM); Clear solution
• Availability: In-stock

Source

Original product source