Facinicline hydrochloride

Overview

Facinicline hydrochloride (RG3487 hydrochloride) is an orally active nicotinic α7 receptor partial agonist, with a K i of 6 nM for α7 human nAChR . Facinicline hydrochloride (RG3487 hydrochloride) improves cognition and sensorimotor gating in rodents. Facinicline hydrochloride (RG3487 hydrochloride) shows high affinity (antagonist) to 5-HT 3 Rs with a K i value of 1.2 nM.

Application

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Product Information

• Catalog No.: HY-108057A
• CAS No.: 677305-02-1
• Molecular Formula: C15H19ClN4O
• Molecular Weight: 306.79
• Purity: 99.66%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 6.25 mg/mL (20.37 mM); Clear solution
• Availability: In-stock

Source

Original product source