2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite

Overview

2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase ( PARP ) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia.

Application

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Product Information

• Catalog No.: HY-W141392
• CAS No.: 2245842-16-2
• Molecular Formula: C40H46FN6O7P
• Molecular Weight: 772.80
• Purity: 98.81%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (3.23 mM); Clear solution
• Availability: In-stock

Source

Original product source