Cemtirestat

Overview

Cemtirestat (CMTI) is a carboxymethylated thiatriazinoindole inhibitor of aldose reductase ( ALR2 ). Cemtirestat potently inhibits rat ocular lens ALR2 with an IC 50 of 0.116 μM, and exhibits a 302-fold selectivity for rat kidney ALR1. Cemtirestat is applicable to the research of advanced diabetic complications.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Glucose Metabolism | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Aldose Reductase

Product Information

• Catalog No.: HY-W151897
• CAS No.: 309283-89-4
• Molecular Formula: C11H8N4O2S
• Molecular Weight: 260.27
• Purity: 99.98%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Availability: In-stock

Source

Original product source