Plitidepsin

Overview

Plitidepsin is a cyclic depsipeptide isolated from the marine tunicate Aplidium albicans. Plitidepsin shows potent anticancer activity against a large variety of cultured human cancer cells, inducing apoptosis by triggering mitochondrial cytochrome c release, initiating the Fas/DC95, JNK pathway and activating caspase 3 activation. This agent also inhibits elongation factor 1-a, thereby interfering with protein synthesis, and induces G1 arrest and G2 blockade, thereby inhibiting tumor cell growth. Source summary: Plitidepsin is a marine cyclic peptide with anticancer and antiviral properties, used in oncology and peptide drug research. Order this compound today!

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Inflammation / Immunology | JNK

Product Information

• Catalog No.: B2693-305469
• CAS No.: 137219-37-5
• Molecular Formula: C57H87N7O15
• Molecular Weight: 1110.34
• Purity: >98%
• Storage: Store at -20°C
• Solubility: Soluble in DMSO

Source

Original product source