7-Hydroxy-2,2-dimethyl-4-chromanone (compound 41) is an inhibitor of DC-SIGN (Dendritic Cell-Specific Intercellular Adhesion Molecule 3 grabbing non-integrin), with an IC 50 of 4.66 mM. DC-SIGN is the C-type lectin receptor presenting on the surface of both macrophages and dendritic cells.
Products | Products > Disease Areas > Others | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Others | Products > Signaling Pathways > C-type Lectin-like Receptors (CTLRs)
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